Mandal S, Bhattacharya D, Roy S, Bose A, Mandal MC, Choudhury G. Comparative Study of Analgesic Effects of Intraarticular Administration of Equipotent Dose of Morphine and Fentanyl with Bupivacaine and Bupivacaine alone in Arthroscopic ACL Reconstruction. J Recent Adv Pain 2016;2(3):72-76.

Ozone disk nucleolysis is a nonsurgical percutaneous procedure for the treatment of discogenic sciatica, and published success rates of ozone disk nucleolysis vary significantly. This study assesses the outcome difference between two treatment modalities among patients with discogenic sciatica secondary to a herniated disk in Bangladesh: Intradiscal ozone injection and combination therapy with intradiscal ozone and transforaminal triamcinolone and bupivacaine injection.

Prospectively recruited 50 patients (group I) received intradiscal injections of an oxygen–ozone mixture and 150 patients (group II) received identical oxygen– ozone injections, followed by transforaminal triamcinolone 20 mg in 2 mL of 0.25% bupivacaine, in relevant foramen. Discography was noted for each case. All patients underwent follow-up examinations at 1-week, 1-month, and 6-month time points. Clinical outcome was evaluated by using the verbal rating scale (VRS) and modified Macnab method.

According to the modified Macnab method, group II showed “excellent and good” result of about 97, 90, and 88% in 1-week, 1-month and 6-month time points respectively, whereas group I showed 70, 70, and 68% at the same time point. The difference is significant in each time point. Groups I and II demonstrated similar VRS scores prior to intervention, but patients in group II had significantly better VRS pain scores at all three time points.

A combination of transforaminal triamcinolone and local anesthetic with intradiscal ozone provides clearly superior outcomes when compared with ozone therapy alone in discogenic sciatica.

Sardar K, Faruque MO, Das G, Hubbard R, Liang NCH, Finkelstein H, Surange PN, Joshi G. A Comparison of Intradiscal Ozone with Transforaminal Triamcinolone and Bupivacaine to Ozone Therapy alone in the Treatment of Discogenic Sciatica. J Recent Adv Pain 2016;2(3):77-81.

The objective of Chronic Pain Challenge project is designing and construction of a machine-learning system to calculate the dynamic changes to the chronic pain risk score of an individual based on various weighted health behaviors.

The visual analog scale (VAS) and Oswestry Disability Index (ODI) ratings of 218 subjects were studied for dynamic changes based on three weighted health behaviors, physical exercise, nutrition, and depression in order to predict their individual and cumulative impact on severity of chronic pain. The predictive function was used to produce confidence and prediction intervals for the calculation of new VAS and ODI scores using supervised and unsupervised machine-learning algorithms and R programing language for statistical computation.

This 9 months research study resulted in the development of innovative design and construction of a machinelearning program that accurately predicted the changes to standardized tests, such as VAS and ODI based on weighted values for depression score (DS), nutrition score (NS) and physical activity score (PAS). The testing of both extreme and moderate ranges of health behavior values in a variety of subjects and comparison against simple weightage confirmed the accuracy and validity of the program.

Chronic Pain Challenge program is a valid and accurate method in predicting chronic pain risk of an individual based on the engagement in various health behaviors. The Chronic Pain Challenge program can predict and prevent progression of chronic pain and disability by global education and empowerment, thereby disrupting the current health care model with the emerging and accelerating technology.

The Chronic Pain Challenge program is an innovative statistical machine-learning program for chronic pain predictability based on individual's health behavior patterns.

Navani A, Li G. Chronic Pain Challenge: A Statistical Machine-learning Method for Chronic Pain Assessment. J Recent Adv Pain 2016;2(3):82-86.

Gurumoorthi R, Vanathi N. Sacroiliac Joint Injection. J Recent Adv Pain 2016;2(3):87-89.

Sardar K, Rashid MA, Khandoker MR, Khan ANMN. Anticonvulsants and Antidepressants in Chronic Pain Management. J Recent Adv Pain 2016;2(3):90-93.

Hendler N. Why Chronic Pain Patients are Misdiagnosed 40 to 80% of the Time? J Recent Adv Pain 2016;2(3):94-98.

Kulkarni R, Das G. Management of Chronic Pain in Children. J Recent Adv Pain 2016;2(3):99-101.

The aim of this study is to investigate scrambler therapy as a modality of treatment for chronic pain.

Four patients with chronic drugresistant severe pain were treated with scrambler therapy, a new bioengineering-based method for treating pain, especially neuropathic pain. The effectiveness of the treatment was evaluated using numeric rating score (NRS); reduction in amount of pain medications and side effects if any were also noted. Each patient was given 10 cycles (or the number of cycles required for complete pain relief) of 30 minutes duration each, and the above parameters were noted.

Three of the four patients had chronic neuropathic pain, and the fourth patient had somatic (bony) pain. All of them showed more than 80% reduction in their pain scores and reduction in the consumption of pain medications.

Kashyap K, Varghese S, Bhatnagar S. Scrambler Therapy for Treatment of Chronic Nonmalignant Pain. J Recent Adv Pain 2016;2(3):102-105.

Soni D, Das G, Datta M. Atypical Presentation of Cervical Facet Arthropathy: Neck Pain along with Numbness and Weakness of Upper Limb. J Recent Adv Pain 2016;2(3):106-108.

Shivhare P, Chansoria M, Vyas A, Dalal A. Single Injection Combined Femoral Sciatic Nerve Block in Lower Limb Orthopedic Surgery in a High-risk Patient. J Recent Adv Pain 2016;2(3):109-111.

Shekhar S, Chansoria M, Singh M, Khandelwal S. Intraperitoneal Instillation of Ropivacaine for Postoperative Pain Relief in Laparoscopic Cholecystectomy in a Comorbid Patient. J Recent Adv Pain 2016;2(3):112-114.