Journal on Recent Advances in Pain

Register      Login

VOLUME 1 , ISSUE 1 ( May-August, 2015 ) > List of Articles

RESEARCH ARTICLE

Comparison between Additive Doses of Fentanyl and Clonidine to Lignocaine with Adrenaline in Lower Limb Surgeries under Lumbar Plexus/Sciatic Block

Ashish Sethi, Arvind Kumar Rathiya

Citation Information : Sethi A, Rathiya AK. Comparison between Additive Doses of Fentanyl and Clonidine to Lignocaine with Adrenaline in Lower Limb Surgeries under Lumbar Plexus/Sciatic Block. J Recent Adv Pain 2015; 1 (1):18-23.

DOI: 10.5005/jp-journals-10046-0006

Published Online: 01-12-2017

Copyright Statement:  Copyright © 2015; The Author(s).


Abstract

Introduction

There are situations in which block anesthesia would be the technique of choice, if the technique or techniques of blocking the lumbar and sacral plexus could be simplified, as they have been for brachial plexus.

Aims and objectives

Aim of the study is to evaluate the effect of adding fentanyl and clonidine to Lignocaine with adrenaline in lumbar/sciatic block with regard to the following parameters: onset of complete motor and sensory block, duration of motor and sensory block, duration of analgesia, sedative effect of fentanyl and clonidine, hemodynamic changes, complications due to adjuvants and to compare both these adjuvants.

Method study design

Patients were randomly allocated into 2 groups of 30 each.

Groups

Groups L and C (lignocaine with adrenaline + clonidine)— 30 patients received 35 ml lignocaine with adrenaline + 10 ml distilled water diluted clonidine containing 100 μg + 5 ml distilled water, and groups L and F (lignocaine with adrenaline + fentanyl)—30 patients received 35 ml lignocaine with adrenaline + 10 ml distilled water diluted fentanyl containing 100 μg + 5 ml distilled water.

Results

From present study, it can be concluded that Clonidine appears to be better adjuvant for prolongation of anesthesia and analgesia in lower limb surgeries under lumbar plexus/ sciatic block.

How to cite this article

Chansoria M, Rathiya AK, Sethi A, Upadhyay R, Vyas N. Comparison between Additive Doses of Fentanyl and Clonidine to Lignocaine with Adrenaline in Lower Limb Surgeries under Lumbar Plexus/Sciatic Block. J Recent Adv Pain 2015;1(1):18-23.


PDF Share
  1. Practical comments on the use and abuse of cocaine; suggested by its invariably successful employment in more than thousand minor surgical operations. NY Med J.
  2. Hydrochlorate of cocaine. NY Med J 1884;40;643. Quoted by Miller RD (1994) in Anesthesia 4th Edition p. 1563 Churchil Livingstone Newyork.
  3. Lower extremity nerve blocks. Int. Anesthesiol. Clin 1963;1:745.
  4. The inguinal paravascular technique of lumbar plexus anesthesia: the ‘3-in-1’ block. Anesth Analg (Cleve.) 1973;52:989.
  5. Anesthesiol Rev 1974;1:11.
  6. Clinical pharmacokinetics of local anesthetics. Can Anaesth Soc J 1977;24:252-262.
  7. Anesth Analg 1977;56:852-861.
  8. The psoas compartment block. Anesthesiol 1976;45:95-99.
  9. There is some evidence for a small number of opioid receptors on axons of peripheral nerves, and addition of different opioids enhance peripheral nerve block from local anesthetics in some studies 25 to 31. Does the addition of morphine to brachial plexus block improve analgesia after shoulder surgery?. Br J Anaesth 1995;75:23-26.
  10. The influence of adjuvants used in regional anesthesia on lidocaine-induced neurotoxicity in vitro. Regional Anesthesia and Pain Med 2011;36(5):436-443.
  11. Value of single-injection or continuous sciatic nerve block in addition to a continuous femoral nerve block in patients undergoing total knee arthroplasty: a prospective, randomized, controlled trial. Reg Anesth Pain Med 2011;36(5):481-488.
  12. Simple regional nerve block for surgery of hand and forearm. JAMA 1956;164:941.
  13. J Chitwan Med College 2013;3(3).
  14. Lumbar plexus block in children: a comparison of two procedures in 50 patients. Anesth Analg 1988 Aug;67(8):750-758.
  15. Anatomy of the posterior approach to the lumbar plexus block. Can J Anaesth 1994 Jun;41(6):480-485.
  16. Posterior approach to the lumbar plexus combined with a Sciatic nerve block using lignocaine. Can J Anaesth 1994 Jun;41(6):486-491.
  17. A clinical study comparing epinephrine 200 μg or clonidine 90 μg as adjuvants to local anaesthetic agent in brachial plexus block via supraclavicular approach. J Anaesthesiol Clin Pharmacol 2010 Oct-Dec;26(4):523-527.
  18. Addition of clonidine or dexmedetomidine to bupivacaine prolongs caudal analgesia in children. Oxford J Med BJA 103;4:617.
  19. Clonidine: an adjunct in isoflurane N2O/O2 relaxant anaesthesia. Effects on EEG power spectra, somatosensory and auditory evoked potentials. Anaesthesia 1995 Apr;50(4):290-296.
  20. Fentanyl supplement expedites the onset time of sensory and motor blocking in interscalene lidocaine anesthesia Daru. 2010;18(4):298-302.
  21. Can J Anaesth 1991;38:870-875.
  22. Effect of adding Fentanyl and/or clonidine to local anaesthetic on prolongation of the peribulbar block in cataract surgery. Ain Shams J Anaesthesiol 2011 Oct;4-3.
  23. Clonidine prolongs the effect of ropivacaine for axillary brachial plexus blockade. Can J Anaesth 2000;47(10):962-967.
  24. Alpha 2-adrenergic agonists for regional anaesthesia: a clinical review of clonidine. Anesthesiol 1984-1995;85(3):655-674.
  25. Gupta T. Comparison of bupivacaine alone and in combination with fentanyl or pethidine for bilateral infraorbital nerve block. J Anaesthesiol Clin Pharmacol 2011;27(1):23-26.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.