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VOLUME 6 , ISSUE 1 ( January-April, 2020 ) > List of Articles


A Comparative Study of Dexmedetomidine and Fentanyl as Adjuvants with Bupivacaine in Adductor Canal Block Regional Anesthesia in Total Knee Replacement Surgery

Channabasava Patil, Chaitra Venkategowda, Narasimha Reddy

Keywords : Adductor canal block, Bupivacaine, Dexmedetomidine, Fentanyl

Citation Information : Patil C, Venkategowda C, Reddy N. A Comparative Study of Dexmedetomidine and Fentanyl as Adjuvants with Bupivacaine in Adductor Canal Block Regional Anesthesia in Total Knee Replacement Surgery. J Recent Adv Pain 2020; 6 (1):4-9.

DOI: 10.5005/jp-journals-10046-0156

License: CC BY-NC 4.0

Published Online: 25-08-2013

Copyright Statement:  Copyright © 2020; The Author(s).


Background/objectives: Total knee replacement surgeries being the ultimate operative modality are commonly performed for severe osteoarthritis. The challenges for the anesthesiologists are to provide optimal postoperative analgesia with minimum motor blockade, so that the patients can be ambulated early, thereby minimizing the complications of delayed ambulation. Materials and methods: We compared the efficacy of fentanyl and dexmedetomidine in improving the analgesic efficacy of bupivacaine-driven regional anesthesia adductor canal block (ACB) in 60 patients who underwent total knee replacement surgeries. We conducted a randomized study of two different drug formulations for the same procedure with random allocation using a computerized table. Results: The visual analog scale (VAS) score of the patients was less in group D. The number of steps walked and the time taken to stand from supine position was better in group D. The amount of local anesthetic requirement was less in group D. Nonsteroidal anti-inflammatory drug (NSAID) requirement was comparable in both the groups. Conclusion: In our study, we observed that VAS score is less in group D, thereby promoting early ambulation and better patient satisfaction. Hence, dexmedetomidine is a better adjuvant than fentanyl for regional anesthesia.

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