Cryoneurolysis by means of using low temperatures reversibly ablates the nerves and provides good analgesia. The duration varies from few months to 1 year. Genitofemoral neuralgia is mainly an iatrogenic neuropathy. With growing knowledge and technique, ultrasound-guided cryoneurolysis of the genitofemoral nerve is a safe and effective measure to treat genitofemoral neuralgia. We are reporting a case of successful cryoablation of the genitofemoral nerve using ultrasound in a patient with chronic inguinal pain after vulvectomy for vulvar cancer extending to the anorectal sphincter. After surgery, the patient was suffering from burning pain around the upper and medial side of the thigh. This was not getting relieved by oral analgesics. The verbal response scale (VRS) was still 8 on analgesics. So, we decided to go for cryoneurolysis of the genitofemoral nerve.
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