Indian Journal of Respiratory Care

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VOLUME 13 , ISSUE 1 ( January-March, 2024 ) > List of Articles

Original Article

Prospective Observational Study on Assessing Medication Reconciliation and Health-related Quality of Life for Chronic Obstructive Pulmonary Disease: Emerging Role of Pharmacists

Ayaana Jain, Shruti Gurav, Joshua T Joseph, Schulen Dias, Shashikala Wali, Revana S Devarinti

Keywords : Clinical pharmacist, Chronic obstructive pulmonary disease, Counseling, Medication discrepancy, Quality of life

Citation Information : Jain A, Gurav S, Joseph JT, Dias S, Wali S, Devarinti RS. Prospective Observational Study on Assessing Medication Reconciliation and Health-related Quality of Life for Chronic Obstructive Pulmonary Disease: Emerging Role of Pharmacists. Indian J Respir Care 2024; 13 (1):3-9.

DOI: 10.5005/jp-journals-11010-1084

License: CC BY-NC 4.0

Published Online: 06-04-2024

Copyright Statement:  Copyright © 2024; The Author(s).


Aim and background: Chronic obstructive pulmonary disease (COPD) is a sustained obstructive airway disease that impedes normal breathing function. The most effective course of action, as deemed by clinical pharmacists, is the implementation of pulmonary rehabilitation, analyzing patient medication charts, efficacy, and safety of medications, improving/enhancing the quality of life, counseling or educating patients, etc. The aim of the present study is to evaluate medication discrepancies and provide counseling to patients to gauge the impact of pulmonary rehabilitation on their health-related quality of life (HRQoL). Materials and methods: A prospective observational study was conducted for 6 months in the Department of General Medicine and Respiratory at a tertiary care hospital. Patients aged >18 years who admitted having a history of COPD were recruited. Further, the best possible medication history (BPMH) was noted, and patients were counseled to compare the quality of life in COPD patients in the pretest and posttest using the SF-36 HRQoL questionnaire. The statistical method used was the dependent t-test. Results: A total of N = 185 patients were screened in accordance with the study's criteria, and N = 103 were enrolled. We identified that the most significant variations occurred when bronchodilator dosage schedules were prescribed upon discharge, and comparisons were made to measure quality of life. In the follow-up, there was an improvement in all domains of quality of life. The pre- and posttest scores were subjected to comparison, and an enhancement in the quality of life was documented (p-value: 0.0001). Conclusion: This study explains the pharmacist's intervention in poststudy. A significant decrease in discrepancies was found, and counseling patients helped improve the quality of life among COPD patients. Clinical significance: This study signifies the emerging role of clinical pharmacists in reviewing medication charts, identifying and resolving drug related problems, and educating patients to improve their quality of life.

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  1. Ritchie AI, Wedzicha JA. Definition, causes, pathogenesis, and consequences of chronic obstructive pulmonary disease exacerbations. Clin Chest Med 2020;41(3):421–438. DOI: 10.1016/j.ccm.2020.06.007
  2. Qaseem A, Wilt TJ, Weinberger SE, et al. Diagnosis and management of stable chronic obstructive pulmonary disease: a clinical practice guideline update from the American College of Physicians, American College of Chest Physicians, American Thoracic Society, and European Respiratory Society. Ann Intern Med 2011;155(3):179–191. DOI: 10.7326/0003-4819-155-3-201108020-00008
  3. Roche N, Chavannes NH, Miravitlles M. COPD symptoms in the morning: impact, evaluation and management. Respir Res 2013;14(1):112. DOI: 10.1186/1465-9921-14-112
  4. Barnsteiner JH. Patient Safety and Quality: An Evidence-Based Handbook for Nurses. Rockville (MD): Agency for Healthcare Research and Quality (US); 2008.
  5. COPD Working Group. Pulmonary rehabilitation for patients with chronic pulmonary disease (COPD): an evidence-based analysis. Ont Health Technol Assess Ser 2012;12(6):1–75.
  6. Devine JF. Chronic obstructive pulmonary disease: an overview. Am Health Drug Benefits 2008;1(7):34–42.
  7. Burge S, Wedzicha JA. COPD exacerbations: definitions and classifications. Eur Respir J Suppl 2003;41:46s–53s. DOI: 10.1183/09031936.03.00078002
  8. Vogelmeier CF, Román-Rodríguez M, Singh D, et al. Goals of COPD treatment: focus on symptoms and exacerbations. Respir Med 2020;166:105938. DOI: 10.1016/j.rmed.2020.105938
  9. Welte T, Vogelmeier C, Papi A. COPD: early diagnosis and treatment to slow disease progression. Int J Clin Pract 2015;69(3):336–349. DOI: 10.1111/ijcp.12522
  10. Smith MC, Wrobel JP. Epidemiology and clinical impact of major comorbidities in patients with COPD. Int J Chron Obstruct Pulmon Dis 2014;9:871–888. DOI: 10.2147/COPD.S49621
  11. Zhong H, Ni XJ, Cui M, et al. Evaluation of pharmacist care for patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis. Int J Clin Pharm 2014;36(6):1230–1240. DOI: 10.1007/s11096-014-0024-9
  12. Suhaj A, Manu MK, Unnikrishnan MK, et al. Effectiveness of clinical pharmacist intervention on health-related quality of life in chronic obstructive pulmonary disorder patients - a randomized controlled study. J Clin Pharm Ther 2016;41(1):78–83. DOI: 10.1111/jcpt.12353
  13. Aryal S, Diaz-Guzman E, Mannino DM. COPD and gender differences: an update. Transl Res 2013;162(4):208–218. DOI: 10.1016/j.trsl.2013.04.003
  14. Diaz-Guzman E, Aryal S, Mannino DM. Occupational chronic obstructive pulmonary disease: an update. Clin Chest Med 2012;33(4):625–636. DOI: 10.1016/j.ccm.2012.07.004
  15. Laniado-Laborín R. Smoking and chronic obstructive pulmonary disease (COPD). Parallel epidemics of the 21 century. Int J Environ Res Public Health 2009;6(1):209–224. DOI: 10.3390/ijerph6010209
  16. Thalla S, Yerubandi A, Hafeezunnisa S, et al. A prospective observational study on acute exacerbation of chronic obstructive pulmonary disease in pulmonology department of tertiary care hospital. Egypt J Bronchol 2020;14. DOI: 10.1186/s43168-020-00047-6
  17. Eisenhower C. Impact of pharmacist-conducted medication reconciliation at discharge on readmissions of elderly patients with COPD. Ann Pharmacother 2014;48(2):203–208. DOI: 10.1177/1060028013512277
  18. van Manen JG, Bindels PJ, Dekker FW, et al. The influence of COPD on health-related quality of life independent of the influence of comorbidity. J Clin Epidemiol 2003;56(12):1177–1184. DOI: 10.1016/s0895-4356(03)00208-7
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