Indian Journal of Respiratory Care

Register      Login

VOLUME 11 , ISSUE 2 ( April-June, 2022 ) > List of Articles

Original Article

Correlation of Radiological Findings on High-Resolution Computed Tomography Chest in Vaccinated and Unvaccinated COVID-19 Patients from Eastern India

Roopak Dubey, Kamal Kumar Sen, Asim Mitra, Humsheer Singh Sethi, Rohit Arora, Mayank Goyal

Keywords : Coronavirus disease-2019, high-resolution computed tomography of the thorax, immunization, vaccination

Citation Information : Dubey R, Sen KK, Mitra A, Sethi HS, Arora R, Goyal M. Correlation of Radiological Findings on High-Resolution Computed Tomography Chest in Vaccinated and Unvaccinated COVID-19 Patients from Eastern India. Indian J Respir Care 2022; 11 (2):124-127.

DOI: 10.4103/ijrc.ijrc_148_21

License: CC BY-NC-SA 4.0

Published Online: 06-12-2022

Copyright Statement:  Copyright © 2022; Indian Journal of Respiratory Care.


Background: In this coronavirus disease-2019 (COVID-19) pandemic, safe and effective preventative vaccines are essential to contain the pandemic, which has had severe medical, economic, and societal consequences, despite some people still becoming infected after receiving immunisation. Methods: A total of 200 patients were examined and split into two groups: (1) 100 consecutive COVID-19-positive cases who had been vaccinated and (2) 100 consecutive COVID-19-positive patients with no vaccination. At the time of the scan, the patient's vaccination status was noted. Results: The computed tomography severity score (CTSS) of unvaccinated individuals was found to be considerably greater than that of partly or fully vaccinated patients (median 13 vs. 7, P < 0.001). Completely vaccinated individuals had a considerably lower median CTSS than partly vaccinated patients (6 vs. 9, P < 0.001). Conclusions: Individuals should be thoroughly vaccinated to avoid major lung disease. As a result, stronger dedication and motivating efforts should be made worldwide to improve the COVID-19 vaccination program.

  1. There have been 7m-13m Excess Deaths Worldwide during the Pandemic. The Economist; 2021. Available from: https://www. deaths-worldwide-during-the-pandemic. [Last accessed on
  2. Tracking SARS-CoV-2 Variants. Available from: https://www.who. int/activities/tracking-SARS-CoV-2-variants. [Last accessed on
  3. Bagcchi S. The world's largest COVID-19 vaccination campaign. Lancet Infect Dis 2021;21:323.
  4. Pilishvili T, Fleming-Dutra KE, Farrar JL, Gierke R, Mohr NM, Talan DA, et al. Interim estimates of vaccine effectiveness of Pfizer- Biontech and Moderna COVID-19 vaccines among health care personnel - 33 U.S. sites, January-March 2021. MMWR Morb Mortal Wkly Rep 2021;70:753-8.
  5. Davies NG, Abbott S, Barnard RC, Jarvis CI, Kucharski AJ, Munday JD, et al. Estimated transmissibility and impact of SARS-CoV-2 lineage B.
  6. 1. 7 in England. Science 2021;372:eabg3055.
  7. Grint DJ, Wing K, Williamson E, McDonald HI, Bhaskaran K, et al. Case fatality risk of the SARS-CoV-2 variant of concern B. 1.1. 7 in England,
  8. Eurosurveillance 2021;26:2100256. [].
  9. Abu-Raddad LJ, Chemaitelly H, Butt AA. Effectiveness of the BNT162b2 COVID-19 vaccine against the B. 1.1. 7 and B. 1.351 Variants. N Engl J Med 2021;385:187-9.
  10. Lopez Bernal J, Andrews N, Gower C, Robertson C, Stowe J, Tessier E, et al. Effectiveness of the Pfizer-BioNTech and Oxford-AstraZeneca vaccines on COVID-19 related symptoms, hospital admissions, and mortality in older adults in England: Test negative case-control study. BMJ 2021;373:n1088.
  11. Singh UB, Rophina M, Chaudhry R, Senthivel V, Bala K, Bhoyar RC, et al. COVID CBNAAT Core Group, Scaria V, Sivasubbu S, Guleria R. Variants of concern responsible for SARS-CoV-2 vaccine breakthrough infections from India. J Med Virol 2022;94:1696-700. [doi: 10.1002/jmv.27461]. Epub 2021 Nov 25. PMID: 34786733; PMCID: PMC8662202.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.