Comparative Evaluation of Mixture of Calcium Hydroxide and Chlorhexidine, with Triple Antibiotic Paste and Combination of Calcium Hydroxide, Chlorhexidine, and Lycopene on Incidence of Interappointment Flare-up: An in vivo Study
Priyanka S Bilgi, Jash Mehta
Citation Information :
Bilgi PS, Mehta J. Comparative Evaluation of Mixture of Calcium Hydroxide and Chlorhexidine, with Triple Antibiotic Paste and Combination of Calcium Hydroxide, Chlorhexidine, and Lycopene on Incidence of Interappointment Flare-up: An in vivo Study. Int J Clin Dent Res 2017; 1 (1):10-14.
The present study was undertaken to evaluate the most suitable intracanal medicament with the least incidence on Interappointment flare-up.
Aim
To clinically evaluate and compare the effect of combination of calcium hydroxide (CH) and chlorhexidine (CHX) with triple antibiotic paste and combination of CH, CHX, and lycopene on interappointment flare-up.
Materials and methods
A total of 36 patients requiring root canal treatment were selected according to the selection criteria and divided into three groups: Group I – CH and CHX, group II – triple antibiotic paste, and group III – CH, CHX, and lycopene. Access opening and biomechanical preparation of all samples, and intracanal medicaments were placed respectively. Subsequently, interappointment flare-up was assessed at 1, 2, 3, 7, and 14 days using verbal rating scale.
Statistical analysis used
One way analysis of variance test and Tukey's post hoc test.
Results
There was no statistically significant difference seen in the clinical performance of CH + CHX, triple antibiotic paste, and mixture of CH + CHX + lycopene at the end of 14 days in terms of interappointment flare-up.
Conclusion
All the intracanal medicaments were effective in reducing interappointment flare-up at the end of 14 days.
How to cite this article
Bilgi PS, Shah NC, Mehta J. Comparative Evaluation of Mixture of Calcium Hydroxide and Chlorhexidine, with Triple Antibiotic Paste and Combination of Calcium Hydroxide, Chlorhexidine, and Lycopene on Incidence of Interappointment Flare-up: An in vivo Study. Int J Clin Dent Res 2017;1(1):10-14.
Incidence of postoperative pain following intracanal procedures based on an antimicrobial strategy. J Endod 2002 Jun;28(6):457-460.
Microbial causes of endodontic flare-ups. Int Endod J 2003 Jul;36(7):453-463.
Antimicrobial effect of calcium hydroxide as an intracanal medicament in root canal treatment: a literature review – part I. In vitro studies. Restor Dent Endod 2014 Nov;39(4):241-252.
Detoxification of endotoxin by endodontic irrigants and calcium hydroxide. J Endod 2001 May;27(5):325-327.
Effect of addition of lycopene to calcium hydroxide and chlorhexidine as intracanal medicament on fracture resistance of radicular dentin at two different time intervals: an in vitro study. J Conserv Dent 2015 May-Jun;18(3):205-209.
Use of triple antibiotic paste as a disinfectant for a traumatized immature tooth with a periapical lesion: a case report. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2009 Aug;108(2):e62-e65.
Antimicrobial effects of triantibiotic paste in endodontic treatment of chronic apical periodontitis. Sch J Dent Sci 2015 Dec-Feb;2(1):58-62.
Effect of calcium hydroxide and triple antibiotic paste as intracanal medicaments on the incidence of inter-appointment flare-up in diabetic patients: an in vivo study. J Conserv Dent 2014 May-Jun;17(3):208-211.
Lack of interchangeability between visual analogue and verbal rating pain scales: a cross sectional description of pain etiology groups. BMC Med Res Methodol 2005 Oct;5:31.
Medicaments: aids to success in endodontics. Part 2. Clinical recommendations. Aust Dent J 1990 Dec;35(6):491-496.
Evaluation of time required for recontamination of coronally sealed canals medicated with calcium hydroxide and chlorhexidine. Int Endod J 2003 Sep;36(9):604-609.
Effect of prophylactic amoxicillin on endodontic flare-up in asymptomatic, necrotic teeth. J Endod 2001 Jan;27(1):53-56.
Bioactivity and protective effects of natural carotenoids. Biochim Biophys Acta 2005 May;1740(2):101-107.
Counteraction of reactive oxygen species and determination of antibacterial efficacy of proanthocyanidin and lycopene when mixed with calcium hydroxide and chlorhexidine mixture: an in vitro comparative study. J Conserv Dent 2012 Oct;15(4):337-341.
In vitro evaluation of the antimicrobial activity of calcium hydroxide combined with chlorhexidine gel used as intracanal medicament. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006 Oct;102(4):544-550.
Comparative evaluation of propolis and triantibiotic mixture as an intracanal medicament against Enterococcus faecalis. J Endod 2011 Sep;37(9):1287-1289.
Sterilization of infected root-canal dentine by topical application of a mixture of ciprofloxacin, metronidazole and minocycline in situ. Int Endod J 1996 Mar;29(2):118-124.
