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MGM Journal of Medical Sciences

Article Details

2017 | January-March | Issue1
ORIGINAL ARTICLE
Utility of GeneXpert Mycobacterium tuberculosis/Rifampin Assay for Extrapulmonary Tuberculosis Samples
Shamma Shetye, Pratiksha Chheda, Ashish Lad, Sunmeet Matkar, Priyanka Yadav
Author Affiliation
Shamma Shetye : Metropolis Healthcare Ltd, Mumbai, Maharashtra, India

Pratiksha Chheda : Metropolis Healthcare Ltd, Mumbai, Maharashtra, India

Ashish Lad : Metropolis Healthcare Ltd, Mumbai, Maharashtra, India

Sunmeet Matkar : Metropolis Healthcare Ltd, Mumbai, Maharashtra, India

Priyanka Yadav : Metropolis Healthcare Ltd, Mumbai, Maharashtra, India

10.5005/jp-journals-10036-1129

ABSTRACT

A total of 3,806 samples from suspected cases of extrapulmonary tuberculosis (EPTB) were subjected to GeneXpert Mycobacterium tuberculosis (MTB)/rifampin (RIF) assay. Samples consisted of body fluids, pleural fluids, pus and aspirates, lymph node (LN) tissues, and others. Mycobacterium tuberculosis positivity was detected in 18.10% and RIF positivity in 2.73% samples. The MTB/RIF positivity was found highest in pus and aspirates (40.38%). In this study, assay failure rate for GeneXpert MTB/RIF assay was very low (1.99%). It is concluded from this study that GeneXpert MTB/RIF is an efficient, reliable, simple, and fast technique for rapid diagnosis of EPTB in our country where incidence of tuberculosis remains high.

Keywords: Assay failure rate, Extrapulmonary tuberculosis, GeneXpert MTB/RIF assay, Positivity rate.

How to cite this article: Shetye S, Chheda P, Lad A, Matkar S, Yadav P. Utility of GeneXpert Mycobacterium tuberculosis/ Rifampin Assay for Extrapulmonary Tuberculosis Samples. MGM J Med Sci 2017;4(1):6-9.

Source of support: Nil

Conflict of interest: None

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