Article Details

2015 | January-March | Issue1
Review Article
Male Infertility: Present and Future
Indrashis Bhattacharya, Subeer S Majumdar
Author Affiliation
Indrashis Bhattacharya : Hemwati Nandan Bahuguna Garhwal University, Srinagar, Uttarakhand, India

Subeer S Majumdar : Cellular Endocrinology Laboratory, Embryo Biotechnology Laboratory, Primate Research Center, National Institute of Immunology, New Delhi, India

10.5005/jp-journals-10036-1039

ABSTRACT

During the last decade, a sudden decline in human male fertility has become a global concern. Genetic, endocrine and life style related problems are generally considered to be the underlie causes. However, several cases have been reported where hormones fail to promote spermatogenesis. The reason of such reproductive malfunctioning leading to male infertility remains idiopathic. Therefore, a sincere attention with a coordinated multidisciplinary effort by the andrologists, urologists and basic scientists is needed to understand the regulation of the sperm production. Powerful tools like high through put gene expression analyses, genetically manipulated mouse models and tissue culture or transplantation based assays are now available, increasing the scope of a establishing a special line of therapy for idiopathic male infertility. In this review, we have briefly summarized various categories of male infertility with emphasis on current research advancement in this field.

Keywords: Male infertility, Primary testicular failure, Testicular dysgenesis syndrome, Spermatogenesis.

How to cite this article: Bhattacharya I, Majumdar SS. Male Infertility: Present and Future. MGM J Med Sci 2015;2(1): 16-24.

Source of support: UGC, DBT, ICMR.

Conflict of interest: None

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