Aim: This review aims to explore various pharmacological studies carried out on Tinospora cordifolia and exploit the therapeutic utility to combat different diseases.

Background: Guduchi [Tinospora cordifolia (Willd.) Miers] is a precious medicinal plant in Ayurveda, the Indian system of medicine. The plant has long been used in Indian traditional medicine by the tribal and nontribal communities for treating a variety of diseases.

Results: Different pharmacology studies of Guduchi illustrated in this review show that this medicinal plant possesses antidiabetic, antioxidant, cognition, anti-inflammatory, analgesic, and wound-healing, anticancer, antimalarial, immunomodulatory, and hepatoprotective activities.

Conclusion: The present review confirms the effectiveness of Guduchi (Tinospora cordifolia) in the prevention and treatment of different health ailments. However, an extensive research and development work on the herb targeting drug characterization and exploring their mechanism of action is essential for validating its potential in preventing and treatment of diseases.

Clinical significance: Tinospora cordifolia showed excellent antihyperglycemic, hypoglycemic, anti-inflammatory, and hepatoprotective activity. It also has beneficial effects on immune modulation for diabetic foot ulcer healing.

Keywords: Analgesic, Anti-inflammatory, Guduchi, Medicinal properties.

How to cite this article: Upadhayay S, Bora M, Kawlni L, Mukherjee K, Hazra J. Comprehensive Pharmacology Review of Guduchi [Tinospora cordifolia (Willd.) Miers]. J Drug Res Ayurvedic Sci 2018;3(1):48-52.

Source of support: Nil

Conflict of interest: None