Aim: This review aims to provide an up-to-date overview of pharmacological studies of Tithonia diversifolia (Hemsl.) A.Gray. Moreover, the focus of this review is the possible exploitation of this species to treat different diseases and to suggest future investigations.

Background: Tithonia diversifolia (Hemsl.) A.Gray is an important medicinal plant whose leaf is the major organ used alone or in combination with other plants for the treatment of a wide variety of ailments. This plant has been a subject of research interest because of its various indigenous medicinal uses in many countries.

Results: Different pharmacological studies on T. deversifolia show that it possesses antibacterial, antioxidant, anti-inflammatory, antinociception, analgesic, antidiarrheal, antimalarial, antihyperglycemic, and cancer chemopreventive activities due to the presence of different active constituents.

Conclusion: Tithonia diversifolia (Hemsl.) A.Gray extracts and their active constituents should be subjected to detailed mechanistic studies to fully understand the mode of action of the active constituents.

Clinical significance: Till date, there is no scientific literature/ data regarding clinical trials of this plant except preclinical studies on different laboratory animals.

Keywords: Pharmacological studies, Therapeutic uses, Tithonia diversifolia, Traditional medicine.

How to cite this article: Kawlni L, Bora M, Upadhyay SN, Hazra J. Pharmacological Profile of Tithonia diversifolia (Hemsl.) A.Gray: A Comprehensive Review. J Drug Res Ayurvedic Sci 2017;2(3):183-187.

Source of support: Nil

Conflict of interest: None