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International Journal of Keratoconus and Ectatic Corneal Diseases


Since the first publication on collagen corneal cross-linking (CXL) for arresting the progression of keratoconus (KC) by the Dresden group1 several hundreds of publications were published most of them reporting positive results of CXL in arresting the progression of the disease, improvement of uncorrected visual acuity (UCVA) and best spectacle corrected visual acuity (BSCVA), reduction of astigmatism and of maximum keratometry reading (K max) In April 2016, the treatment was approved by the FDA after a controlled randomized study. The beneficial effect of the treatment was reported even after 10 years2 corneal topography, and endothelial cell count (ECC).

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