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International Journal of Infertility & Fetal Medicine


Objective: To determine whether weight loss in obese men improves seminal parameters.

Design: Prospective interventional study.

Setting: Infertility clinic and weight loss centers.

Patient: All men attending infertility center and weight loss programmes from April 2012 to May 2015 (n = 105).

Intervention: Diet counseling and exercise.

Main Outcome Measure: Collected reproductive parameters included semen analysis (ejaculate volume, sperm concentration, progressive and non-progressive motility) data. Body mass index (BMI) was calculated for all patients with comparisons to reproductive parameters before and after weight loss by using paired-t test and Chi-square tests.

Result: The mean BMI was significantly higher before weight loss (33.2) than after weight loss (30.4) in obese men. The weight loss had significant positive correlation with percentage of progressive sperm motility (p = < 0.001) and static percentage (p = < 0.001). Weight loss had non-significant correlation with semen volume (p = 0.083), concentration (p = 0.418) and non progressive motile sperm (p = 0.361).

Conclusion: In one of the largest cohorts of male fertility and obesity, semen parameters demonstrated mild but significant relationships with BMI and semen parameters, possibly contributing to subfertility in this population.

Keywords: Body mass index, Male infertility, Obesity, Semen analysis, Weight loss.

How to cite this article: Jaffar M, Ashraf M. Does Weight Loss improve Fertility with respect to Semen Parameters—esults from a Large Cohort Study. Int J Infertil Fetal Med 2017;8(1): 12-17.

Source of support: Nil

Conflict of interest: None

Date of received: 18-8-2016

Date of acceptance: 30-9-2016

Date of publication: May 2017

© Jaypee Brothers Medical Publishers (P) Ltd.