In human clinical trials and biological experiments, randomization has been extensively used as a method of experimental control. It insures against the accidental bias and helps in preventing the selection bias. In treatment assignments, it eliminates the source of bias and produces the comparable groups, thereby expressing the likelihood of chance as a source for the difference of end outcome by permitting the use of probability theory. This study covers different methods of randomization and the use of online statistical computing web programming www.randomization. com for generating the randomization schedule. Issues related to randomization are also discussed in this study.
Keywords: Block, Covariate, Patient, Qucikcalc, Randomization, Stratified, Treatment.
How to cite this article: Suresh KP, Yasaswini S, Reshma K. Application of Randomization Techniques for an Unbiased Assessment of Outcome in Clinical Studies. Int J Infertil Fetal Med 2016;7(3):94-98.
Source of support: Nil
Conflict of interest: None
Date of received: 17 April 2016
Date of acceptance: 29 May 2016
Date of publication: September 2016